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Home Antibody All anti-SECISBP2 antibodies

Anti-SECISBP2 Antibody

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA303146
  • Goat Polyclonal Antibody against SECISBP2
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC411333) , 20ug Explanation
100ug 325 3-7 Days
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WB(1)
IHC(1)
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Also for SECISBP2 (NM_024077)
cDNA Clone shRNA/siRNA Lysate Protein Request Antibody

OriGene Data

Immunogen Peptide with sequence C-KERQERKQRLQEN, from the internal region of the protein sequence according to NP_076982.3.
Clone Name IsotypeGoat IgG
Species ReactivityTest: Human, Mouse. Expected from seq similarity: Human, Dog, Pig, Cow Concentration0.5 mg/ml
Guaranteed Application *WB, IHC Suggested DilutionsELISA: 1:64,000. WB: 0.1-0.3µg/ml. IHC: 3µg/ml.
BufferSupplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Purification Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing.

Reference Data

Target NameHomo sapiens SECIS binding protein 2 (SECISBP2), transcript variant 1
Alternative NameSBP2
Database LinkNP_076982
Entrez Gene 79048 Human
Entrez Gene 75420 Mouse
Entrez Gene 476351 Dog
FunctionThe incorporation of selenocysteine into a protein requires the concerted action of an mRNA element called a sec insertion sequence (SECIS), a selenocysteine-specific translation elongation factor and a SECIS binding protein. With these elements in place, a UGA codon can be decoded as selenocysteine. The gene described in this record encodes a nuclear protein that functions as a SECIS binding protein. Mutations in this gene have been associated with a reduction in activity of a specific thyroxine deiodinase, a selenocysteine-containing enzyme, and abnormal thyroid hormone metabolism. [provided by RefSeq]. COMPLETENESS: complete on the 3' end.
Related Pathway

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
TA303146 staining of HFF cell lysate with B) 100nM siRNA or A) control siRNA. Detected by chemiluminescence. Data kindly provided by Laura Papp and Kum Kum Khanna, Brisbane, Australia.
IHC Image
TA303146 (3µg/ml) staining of paraffin embedded Human Testis. Microwaved antigen retrieval with Tris/EDTA buffer pH9, HRP-staining.

 

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