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Home Antibody All anti-GPX4 antibodies

Anti-GPX4 Antibody

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SKU Description Amount Price Availability*  
TA303125 Goat Polyclonal Antibody against GPX4 100ug $325 3-7 Days
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WB(1)
IHC(1)

OriGene Data

Immunogen Peptide with sequence C-EEPLVIEKDLPHY, from the C Terminus of the protein sequence according to NP_002076.2; NP_001034937.1.
Clone Name IsotypeGoat IgG
Species ReactivityTest: Human. Expected from seq similarity: Human, Mouse, Rat, Pig, Cow Concentration0.5 mg/ml
Guaranteed Application *WB, IHC Suggested DilutionsELISA: 1:16,000. WB: 0.1-0.3µg/ml. IHC: 0.3µg/ml.
BufferSupplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Purification Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing.

Reference Data

Target NameHomo sapiens glutathione peroxidase 4 (GPX4), transcript variant 2
Alternative NameGPx-4; GSHPx-4; MCSP; PHGPx; snGPx; snPHGPx
Database LinkNP_001034936
Entrez Gene 2879 Human
Entrez Gene 625249 Mouse
Entrez Gene 29328 Rat
FunctionGlutathione peroxidase catalyzes the reduction of hydrogen peroxide, organic hydroperoxide, and lipid peroxides by reduced glutathione and functions in the protection of cells against oxidative damage. Human plasma glutathione peroxidase has been shown to be a selenium-containing enzyme and the UGA codon is translated into a selenocysteine. Through alternative splicing and transcription initiation, rat produces proteins that localize to the nucleus, mitochondrion, and cytoplasm. In humans, experimental evidence for alternative splicing exists; alternative transcription initiation and the cleavage sites of the mitochondrial and nuclear transit peptides need to be experimentally verified. [provided by RefSeq].
Related PathwayDruggable Genome Glutathione metabolismArachidonic acid metabolism

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

TA303125 (0.1µg/ml) staining of Human Testis lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
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TA303125 (0.3µg/ml) staining of paraffin embedded Human Testis. Microwaved antigen retrieval with citrate buffer pH 6, HRP-staining.
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