Homo sapiens adrenergic, beta-1-, receptor (ADRB1)
Synonyms:
ADRB1R; B1AR; BETA1AR; RHR
Immunogen
Peptide with sequence ESDEARRCYNDPK, from the internal region of the protein sequence according to NP_000675.1.
Buffer
Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Clone Name
Isotype
Goat IgG
Species Reactivity
Human
Concentration
0.5 mg/ml
Purification
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing.
Guaranteed Application *
WB
Suggested Dilutions
Peptide ELISA: antibody detection limit dilution 1:128,000. Western blot recommended concentration: 0.3-1µg/ml.
Background
The adrenergic receptors (subtypes alpha 1, alpha 2, beta 1, and beta 2) are a prototypic family of guanine nucleotide binding regulatory protein-coupled receptors that mediate the physiological effects of the hormone epinephrine and the neurotransmitter norepinephrine. Specific polymorphisms in this gene have been shown to affect the resting heart rate and can be involved in heart failure. [provided by RefSeq].
Related Pathway
Signaling by GPCR
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