Home Antibody All anti-ADRBK1 antibodies
Also for ADRBK1 (NM_001619)
| Peptide with sequence C-RDAYREAQQLVQR, from the internal region of the protein sequence according to NP_001610.1.|
||ELISA: 1:16,000. WB: 0.3-1.0µg/ml.
|Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.|
| Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing.
|Homo sapiens adrenergic, beta, receptor kinase 1 (ADRBK1)|
|BARK1; BETA-ARK1; GRK2|
|The product of this gene phosphorylates the beta-2-adrenergic receptor and appears to mediate agonist-specific desensitization observed at high agonist concentrations. This protein is an ubiquitous cytosolic enzyme that specifically phosphorylates the activated form of the beta-adrenergic and related G-protein-coupled receptors. Abnormal coupling of beta-adrenergic receptor to G protein is involved in the pathogenesis of the failing heart. [provided by RefSeq]. |
Signaling by GPCR
* Shipping is in business days
* OriGene provides validated application data and protocol, with money back guarantee.
TA303088 (0.3µg/ml) staining of Daudi cell lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.