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Home Antibody All anti-FZD8 antibodies

Anti-FZD8 Antibody

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA303076
  • Goat Polyclonal Antibody against FZD8
100ug 325 In Stock
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WB(1)
IHC(1)

OriGene Data

Immunogen Peptide with sequence C-SYPKQMPLSQV, from the C Terminus of the protein sequence according to NP_114072.1.
Clone Name IsotypeGoat IgG
Species ReactivityHuman Concentration0.5 mg/ml
Guaranteed Application *WB, IHC Suggested DilutionsELISA: 1:32,000. WB: 1-3µg/ml. IHC: 3µg/ml.
BufferSupplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Purification Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing.

Reference Data

Target NameHomo sapiens frizzled class receptor 8 (FZD8)
Alternative NameFZ-8; hFZ8
Database LinkNP_114072
FunctionThis intronless gene is a member of the frizzled gene family. Members of this family encode seven-transmembrane domain proteins that are receptors for the Wingless type MMTV integration site family of signaling proteins. Most frizzled receptors are coupled to the beta-catenin canonical signaling pathway. This gene is highly expressed in two human cancer cell lines, indicating that it may play a role in several types of cancer. The crystal structure of the extracellular cysteine-rich domain of a similar mouse protein has been determined. [provided by RefSeq].
Related Pathway
Melanogenesis
Wnt Signaling Pathway

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WB Image
TA303076 (1µg/ml) staining of human pancreas lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
IHC Image
TA303076 (3µg/ml) staining of paraffin embedded Human Pancreas. Microwaved antigen retrieval with Tris/EDTA buffer pH9, HRP-

 

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