Home Antibody All anti-KLRK1 antibodies
Also for KLRK1 (NM_007360)
| Peptide with sequence C-KVYSKEDQDLLK, from the internal region of the protein sequence according to NP_031386.1.|
|Test: Human. Expected from seq similarity: Human, Mouse, Rat
||ELISA: 1:32,000. WB: 0.1-0.3µg/ml.
|Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.|
| Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing.
|Homo sapiens killer cell lectin-like receptor subfamily K, member 1 (KLRK1)|
|CD314; D12S2489E; KLR; NKG2-D; NKG2D|
Entrez Gene 22914 Human
Entrez Gene 27007 Mouse
Entrez Gene 24934 Rat
|Natural killer (NK) cells are lymphocytes that can mediate lysis of certain tumor cells and virus-infected cells without previous activation. They can also regulate specific humoral and cell-mediated immunity. NK cells preferentially express several calcium-dependent (C-type) lectins, which have been implicated in the regulation of NK cell function. This gene encodes a member of the NKG2 family, and the encoded transmembrane protein is characterized by a type II membrane orientation (extracellular C terminus) and the presence of a C-type lectin domain. The NKG2 gene family is located within the NK complex, a region that contains several C-type lectin genes preferentially expressed in NK cells. [provided by RefSeq]. |
|Transmembrane Natural killer cell mediated cytotoxicity|
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TA303045 staining (0.3µg/ml) of human spleen lysate (RIPA buffer, 35µg total protein per lane). Primary incubated for 1 hour. Detected by western blot using chemiluminescence.