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Home Antibody All anti-NPM1 antibodies

Anti-NPM1 Antibody

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA303008
  • Goat Polyclonal Antibody against NPM1
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC421985) , 20ug Explanation
100ug 325 3-7 Days
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WB(1)
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Also for NPM1 (NM_001037738)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

Immunogen Peptide with sequence C-QEAIQDLWQWRKSL, from the C Terminus of the protein sequence according to NP_002511.1; NP_954654.1.
Clone Name IsotypeGoat IgG
Species ReactivityTest: Human, Mouse, Rat. Expected from seq similarity: Human, Mouse, Rat, Dog, Cow Concentration0.5 mg/ml
Guaranteed Application *WB Suggested DilutionsWB: 0.03-0.1ug/mL
BufferSupplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Purification Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing.

Reference Data

Target NameHomo sapiens nucleophosmin (nucleolar phosphoprotein B23, numatrin) (NPM1), transcript variant 3
Alternative NameB23; NPM
Database LinkNP_001032827
Entrez Gene 4869 Human
Entrez Gene 18148 Mouse
Entrez Gene 25498 Rat
Entrez Gene 479292 Dog
FunctionNPM1 is a ubiquitously expressed nucleolar protein that shuttles between the nucleus and cytoplasm. It is implicated in multiple functions, including ribosomal protein assembly and transport, control of centrosome duplication, and regulation of the tumor suppressor ARF (MIM 600160). NPM1 mutations that relocalize NPM1 from the nucleus into the cytoplasm are associated with development of acute myeloid leukemia (AML; MIM 601626) (Garzon et al., 2008 [PubMed 18308931]).[supplied by OMIM].
Related PathwayStem cell - PluripotencyTranscription FactorsDruggable Genome

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
TA303008 staining (0.1µg/ml) of Jurkat lysate (RIPA buffer, 35µg total protein per lane). Primary incubated for 1 hour. Detected by western blot using chemiluminescence.

 

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