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Home Antibody All anti-RGS14 antibodies

Anti-RGS14 Antibody

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA302943
  • Goat Polyclonal Antibody against RGS14
  • FREE positive control: HEK293T cell transient overexpression lysate (LC416615) , 20ug
100ug $325 In Stock
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WB(1)
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Also for RGS14 (NM_006480)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

Immunogen Peptide with sequence C-IGGSLNSTTDSAL, from the C Terminus of the protein sequence according to NP_006471.
Clone Name IsotypeGoat IgG
Species ReactivityHuman Concentration0.5mg/ml
Guaranteed Application *WB Suggested DilutionsELISA: 1:16,000. WB: 0.5-2µg/ml.
BufferSupplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Purification Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing.

Reference Data

Target NameHomo sapiens regulator of G-protein signaling 14 (RGS14)
Alternative Nameregulator of G-protein signalling 14; regulator of G-protein signaling 14
Database LinkNP_006471
FunctionThis gene encodes a member of the regulator of G-protein signaling family. This protein contains one RGS domain, two Raf-like Ras-binding domains (RBDs), and one GoLoco domain. The protein attenuates the signaling activity of G-proteins by binding, through its GoLoco domain, to specific types of activated, GTP-bound G alpha subunits. Acting as a GTPase activating protein (GAP), the protein increases the rate of conversion of the GTP to GDP. This hydrolysis allows the G alpha subunits to bind G beta/gamma subunit heterodimers, forming inactive G-protein heterotrimers, thereby terminating the signal. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized. COMPLETENESS: complete on the 3' end.
Related Pathway

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WB Image
TA302943 staining (0.5µg/ml) of Jurkat lysate (RIPA buffer, 35µg total protein per lane). Primary incubated for 1 hour. Detected by western blot using chemiluminescence.

 

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