Homo sapiens NADPH oxidase organizer 1 (NOXO1), transcript variant a
P41NOX; P41NOXA; P41NOXB; P41NOXC; SH3PXD5; SNX28
Peptide with sequence RGCVDSVPHPTTEQ, from the C Terminus of the protein sequence according to NP_653204.1; NP_751907.1; NP_751907.1.
Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing. (Protein A or G Sepharose)
Guaranteed Application *
ELISA: 1:16,000. WB: 10-20µg/ml.
NADPH oxidases (NOXs) catalyze the transfer of electrons from NADPH to molecular oxygen to generate reactive oxygen species (ROS). NOX organizers, such as NOXO1, target NOX activators (see NOXA1; MIM 611255) to NOX and also target NOX to different subcellular compartments (Opitz et al., 2007 [PubMed 17189823]).[supplied by OMIM].
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