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Home Antibody All anti-TRIM63 antibodies

Anti-TRIM63 Antibody

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Specifications Citations (0) Related Products Product Documents
SKU Description Amount Price Availability*  
TA302858 Goat Polyclonal Antibody against TRIM63 100ug $325 3-7 Days
LC410019 TRIM63 HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
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IHC(1)

OriGene Data

Immunogen Peptide with sequence DYKSSLIQDGNPM-C, from the N Terminus of the protein sequence according to NP_115977.2.
Clone Name IsotypeGoat IgG
Species ReactivityTest: Human. Expected from seq similarity: Human, Dog, Cow Concentration0.5 mg/ml
Guaranteed Application *IHC Suggested DilutionsELISA: 1:32,000. WB: 0.1µg/ml.
BufferSupplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Purification Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing.

Reference Data

Target NameHomo sapiens tripartite motif containing 63, E3 ubiquitin protein ligase (TRIM63)
Alternative NameIRF; MURF1; MURF2; RNF28; SMRZ
Database LinkNP_115977
Entrez Gene 84676 Human
Entrez Gene 487362 Dog
FunctionThis gene encodes a member of the RING zinc finger protein family found in striated muscle and iris. The product of this gene is localized to the Z-line and M-line lattices of myofibrils, where titin's N-terminal and C-terminal regions respectively bind to the sarcomere. In vitro binding studies have shown that this protein also binds directly to titin near the region of titin containing kinase activity. Another member of this protein family binds to microtubules. Since these family members can form heterodimers, this suggests that these proteins may serve as a link between titin kinase and microtubule-dependent signal pathways in muscle. [provided by RefSeq].
Related Pathway

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

TA302858 (1.25µg/ml) staining of paraffin embedded Human Skeletal Muscle. Steamed antigen retrieval with citrate buffer pH 6, AP-staining.
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