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Home Antibody All anti-TBL1X antibodies

Anti-TBL1X Antibody

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA302762
  • Goat Polyclonal Antibody against TBL1X / TBL1XR1
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC427964) , 20ug
100ug 325 In Stock
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WB(1)
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Also for TBL1X (NM_001139466)
cDNA Clone shRNA/siRNA Lysate Protein Request Antibody

OriGene Data

Immunogen Peptide with sequence SASDGSVCVLDLRK, from the C Terminus of the protein sequence according to NP_005638.1; NP_078941.2.
Clone Name IsotypeGoat IgG
Species ReactivityHuman ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB Suggested DilutionsWB: 3-5µg/ml.
BufferSupplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Purification Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing.

Reference Data

Target NameHomo sapiens transducin (beta)-like 1X-linked (TBL1X), transcript variant 2
Alternative NameEBI; SMAP55; TBL1
Database LinkNP_001132938
FunctionThe protein encoded by this gene has sequence similarity with members of the WD40 repeat-containing protein family. The WD40 group is a large family of proteins, which appear to have a regulatory function. It is believed that the WD40 repeats mediate protein-protein interactions and members of the family are involved in signal transduction, RNA processing, gene regulation, vesicular trafficking, cytoskeletal assembly and may play a role in the control of cytotypic differentiation. This encoded protein is found as a subunit in corepressor SMRT (silencing mediator for retinoid and thyroid receptors) complex along with histone deacetylase 3 protein. This gene is located adjacent to the ocular albinism gene and it is thought to be involved in the pathogenesis of the ocular albinism with late-onset sensorineural deafness phenotype. Four transcript variants encoding two different isoforms have been found for this gene. This gene is highly similar to the Y chromosome TBL1Y gene. [provided by RefSeq].
Related Pathway
Wnt Signaling Pathway

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WB Image
TA302762 staining (4µg/ml) of Human Brain lysate (RIPA buffer, 35µg total protein per lane). Primary incubated for 1 hour. Detected by western blot using chemiluminescence.

 

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