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Home Antibody All anti-DDB1 antibodies

Anti-DDB1 Antibody

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Specifications Citations (0) Related Products Product Documents
SKU Description Amount Price Availability*  
TA302707
  • Goat Polyclonal Antibody against DDB1
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC419658) , 20ug Explanation
100ug $325 3-7 Days
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WB(1)

OriGene Data

Immunogen Peptide with sequence C-DLIKVVEELTRIH, from the C Terminus of the protein sequence according to NP_001914.
Clone Name IsotypeGoat IgG
Species ReactivityTest: Human, Mouse. Expected from seq similarity: Human, Mouse, Rat, Dog, Cow Concentration0.5 mg/ml
Guaranteed Application *WB Suggested DilutionsWB: 0.2-1 µg/ml.
BufferSupplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Purification Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing.

Reference Data

Target NameHomo sapiens damage-specific DNA binding protein 1, 127kDa (DDB1)
Alternative NameDDBA; UV-DDB1; XAP1; XPCE; XPE; XPE-BF
Database LinkNP_001914
Entrez Gene 1642 Human
Entrez Gene 13194 Mouse
Entrez Gene 64470 Rat
Entrez Gene 476067 Dog
FunctionThis gene encodes the large subunit of DNA damage-binding protein which is a heterodimer composed of a large and a small subunit. This protein functions in nucleotide-excision repair. Its defective activity causes the repair defect in the patients with xeroderma pigmentosum complementation group E (XPE). However, it remains for mutation analysis to demonstrate whether the defect in XPE patients is in this gene or the gene encoding the small subunit. In addition, Best vitelliform mascular dystrophy is mapped to the same region as this gene on 11q, but no sequence alternations of this gene are demonstrated in Best disease patients. [provided by RefSeq].
Related PathwayDruggable Genome Nucleotide excision repairUbiquitin mediated proteolysis

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

TA302707 (1 µg/ml) staining of NSO lysate (1E5 cells per lane). Detected by western blot using chemiluminescence.
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