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Home Antibody All anti-RACGAP1 antibodies

Anti-RACGAP1 Antibody

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Specifications Citations Customer Reviews Product Documents
SKU Description Amount Price Availability*  
TA302684 Goat Polyclonal Antibody against RACGAP1 / MgcRacGAP 100ug $325 3-7 Days
LC402238 RACGAP1 HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
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WB(1)
IHC(1)
IF(1)
FC(1)
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Also for RACGAP1 (NM_013277)
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OriGene Data

ImmunogenPeptide with sequence C-GRQGNFFASPMLK, from the C Terminus of the protein sequence according to NP_037409.1.
Clone Name IsotypeGoat IgG
Species ReactivityTest: Human. Expected from seq similarity: Human, Dog, Cow Concentration0.5 mg/ml
Guaranteed Application *WB, IHC, IF, FC Suggested DilutionsWB: 0.2-1µg/ml.
Predicted MW Explanation 70.8 kDa
BufferSupplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Purification Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.

Reference Data

Target NameHomo sapiens Rac GTPase activating protein 1 (RACGAP1), transcript variant 1
Alternative NameCYK4; HsCYK-4; ID-GAP; MgcRacGAP
Database LinkNP_037409
Entrez Gene 29127 Human
Entrez Gene 486549 Dog
FunctionRho GTPases control a variety of cellular processes. There are 3 subtypes of Rho GTPases in the Ras superfamily of small G proteins: RHO (see MIM 165370), RAC (see RAC1; MIM 602048), and CDC42 (MIM 116952). GTPase-activating proteins (GAPs) bind activated forms of Rho GTPases and stimulate GTP hydrolysis. Through this catalytic function, Rho GAPs negatively regulate Rho-mediated signals. GAPs may also serve as effector molecules and play a role in signaling downstream of Rho and other Ras-like GTPases.[supplied by OMIM].
Related PathwayDruggable Genome

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.


WB Image
TA302684(1µg/ml) staining of A431 nuclear (A), Jurkat (B), Jurkat nuclear (C) and negative control Human Pancreas (D) lysate. (35µg protein in RIPA buffer) Detected by chemiluminescence.
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IHC Image
TA302684(4µg/ml) staining of paraffin embedded Human Testis. Microwaved antigen retrieval with Tris/EDTA buffer pH9, HRP-staining.
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IF Image
TA302684 Immunofluorescence analysis of paraformaldehyde fixed MCF7 cells, permeabilized with 0.15% Triton. Primary incubation 1hr (10ug/ml) followed by Alexa Fluor 488 secondary antibody (4ug/ml), showing nuclear staining. The nuclear stain is DAPI (blue). Negative control: Unimmunized goat IgG (10ug/ml) followed by Alexa Fluor 488 secondary antibody (4ug/ml).
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FC Image
TA302684 Flow cytometric analysis of paraformaldehyde fixed MCF7 cells (blue line), permeabilized with 0.5% Triton. Primary incubation 1hr (10ug/ml) followed by Alexa Fluor 488 secondary antibody (4ug/ml). IgG control: Unimmunized goat IgG (black line) followed by Alexa Fluor 488 secondary antibody.
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