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Home Antibody All anti-NQO1 antibodies

Anti-NQO1 Antibody

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Specifications Citations (0) Related Products Product Documents
SKU Description Amount Price Availability*  
TA302678 Goat Polyclonal Antibody against NQO1 100ug $325 3-7 Days
LC400327 NQO1 HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock

Buy any antibody of 100ul or more, get a free package of 3 loading control antibody samples. View Details Add to Shopping Cart

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WB(1)

OriGene Data

Immunogen Peptide with sequence C-SIPTDNQIKARK, from the C Terminus of the protein sequence according to NP_000894.1; NP_001020604.1; NP_001020605.1.
Clone Name IsotypeGoat IgG
Species ReactivityTest: Human, Mouse, Dog. Expected from seq similarity: Human, Mouse, Rat, Dog, Pig Concentration0.5 mg/ml
Guaranteed Application *WB Suggested DilutionsELISA: 1:2,000. WB: 1-3µg/ml.
Predicted MW Explanation 30.7 kDa
BufferSupplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Purification Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.

Reference Data

Target NameHomo sapiens NAD(P)H dehydrogenase, quinone 1 (NQO1), transcript variant 1
Alternative NameDHQU; DIA4; DTD; NMOR1; NMORI; QR1
Database LinkNP_000894
Entrez Gene 1728 Human
Entrez Gene 18104 Mouse
Entrez Gene 24314 Rat
Entrez Gene 610935 Dog
FunctionThis gene is a member of the NAD(P)H dehydrogenase (quinone) family and encodes a cytoplasmic 2-electron reductase. This FAD-binding protein forms homodimers and reduces quinones to hydroquinones. This protein's enzymatic activity prevents the one electron reduction of quinones that results in the production of radical species. Mutations in this gene have been associated with tardive dyskinesia (TD), an increased risk of hematotoxicity after exposure to benzene, and susceptibility to various forms of cancer. Altered expression of this protein has been seen in many tumors and is also associated with Alzheimer's disease (AD). Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq].
Related PathwayDruggable Genome

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

TA302678 staining (1µg/ml) of Human Lung lysate (RIPA buffer, 35µg total protein per lane). Primary incubated for 1 hour. Detected by western blot using chemiluminescence.
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