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Home Antibody All anti-XRCC6 antibodies

Anti-XRCC6 Antibody

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Specifications Citations (0) Related Products Product Documents
SKU Description Amount Price Availability*  
TA302668 Goat Polyclonal Antibody against KU70 / XRCC6 100ug $325 3-7 Days
LC400567 XRCC6 HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
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WB(1)
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Also for XRCC6 (NM_001469)
cDNA Clone shRNA/siRNA CRISPR KO Kit Protein Antibody

OriGene Data

Immunogen Peptide with sequence YKTEGDEEAEEEQ-C, from the N Terminus of the protein sequence according to NP_001460.1.
Clone Name IsotypeGoat IgG
Species ReactivityTest: Human. Expected from seq similarity: Human Concentration0.5 mg/ml
Guaranteed Application *WB Suggested DilutionsELISA: 1:2,000. WB: 0.1-0.3µg/ml.
Predicted MW Explanation 69.7 kDa
BufferSupplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Purification Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.

Reference Data

Target NameHomo sapiens X-ray repair complementing defective repair in Chinese hamster cells 6 (XRCC6), transcript variant 1
Alternative NameCTC75; CTCBF; G22P1; KU70; ML8; TLAA
Database LinkNP_001460
Entrez Gene 2547 Human
FunctionThe p70/p80 autoantigen is a nuclear complex consisting of two subunits with molecular masses of approximately 70 and 80 kDa. The complex functions as a single-stranded DNA-dependent ATP-dependent helicase. The complex may be involved in the repair of nonhomologous DNA ends such as that required for double-strand break repair, transposition, and V(D)J recombination. High levels of autoantibodies to p70 and p80 have been found in some patients with systemic lupus erythematosus. [provided by RefSeq].
Related PathwayTranscription FactorsDruggable Genome Non-homologous end-joining

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

TA302668 (0.1µg/ml) staining of HeLa cell lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
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