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Home Antibody All anti-BLNK antibodies

Anti-BLNK Antibody

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA302649
  • Goat Polyclonal Antibody against BLNK
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC402244) , 20ug
100ug 325 3-7 Days
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WB(1)

OriGene Data

Immunogen Peptide with sequence C-KDSTRLKYAVKVS, from the C Terminus of the protein sequence according to NP_037446.1.
Clone Name IsotypeGoat IgG
Species ReactivityTest: Human. Expected from seq similarity: Human, Mouse, Rat, Dog, Pig, Cow Concentration0.5 mg/ml
Guaranteed Application *WB Suggested DilutionsWB: 3-5µg/ml.
BufferSupplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Purification Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.

Reference Data

Target NameHomo sapiens B-cell linker (BLNK), transcript variant 1
Alternative NameAGM4; BASH; bca; BLNK-S; LY57; SLP-65; SLP65
Database LinkNP_037446
FunctionThis gene encodes a cytoplasmic linker or adaptor protein that plays a critical role in B cell development. This protein bridges B cell receptor-associated kinase activation with downstream signaling pathways, thereby affecting various biological functions. The phosphorylation of five tyrosine residues is necessary for this protein to nucleate distinct signaling effectors following B cell receptor activation. Mutations in this gene cause hypoglobulinemia and absent B cells, a disease in which the pro- to pre-B-cell transition is developmentally blocked. Deficiency in this protein has also been shown in some cases of pre-B acute lymphoblastic leukemia. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq].
Related Pathway

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WB Image
TA302649 staining (4µg/ml) of Daudi lysate (RIPA buffer, 30µg total protein per lane). Primary incubated for 1 hour. Detected by western blot using chemiluminescence.

 

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