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Home Antibody All anti-CAV1 antibodies

Anti-CAV1 Antibody


Specifications Citations Customer Reviews Product Documents
SKU Description Amount Price Availability*  
TA302639 Goat Polyclonal Antibody against Caveolin 1 100ug $325 In Stock
LC400664 CAV1 HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
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OriGene Data

Immunogen Peptide with sequence C-DELSEKQVYDAH, from the internal region of the protein sequence according to NP_001744.2.
Clone Name IsotypeGoat IgG
Species ReactivityTest: Human. Expected from seq similarity: Human, Mouse, Rat, Dog, Pig Concentration0.5mg/ml
Guaranteed Application *WB Suggested DilutionsELISA: 1:8,000. WB: 0.01-0.03ug/ml
Predicted MW Explanation 20.3 kDa
BufferSupplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Purification Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.

Reference Data

Target NameHomo sapiens caveolin 1, caveolae protein, 22kDa (CAV1), transcript variant 1
Alternative NameBSCL3; CGL3; LCCNS; MSTP085; PPH3; VIP21
Database LinkNP_001744
Entrez Gene 857 Human
Entrez Gene 12389 Mouse
Entrez Gene 25404 Rat
Entrez Gene 403980 Dog
FunctionThe scaffolding protein encoded by this gene is the main component of the caveolae plasma membranes found in most cell types. The protein links integrin subunits to the tyrosine kinase FYN, an initiating step in coupling integrins to the Ras-ERK pathway and promoting cell cycle progression. The gene is a tumor suppressor gene candidate and a negative regulator of the Ras-p42/44 MAP kinase cascade. CAV1 and CAV2 are located next to each other on chromosome 7 and express colocalizing proteins that form a stable hetero-oligomeric complex. By using alternative initiation codons in the same reading frame, two isoforms (alpha and beta) are encoded by a single transcript from this gene. [provided by RefSeq].
Related PathwayTransmembraneDruggable Genome Focal adhesionViral myocarditis

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
TA302639 (0.3µg/ml) staining of human spleen lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.


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