Home Antibody All anti-ATF4 antibodies
Also for ATF4 (NM_001675)
| Peptide with sequence C-EEVRKARGKKRVP, from the C Terminus of the protein sequence according to NP_001666.|
|Test: Human, Mouse. Expected from seq similarity: Human, Mouse, Rat, Pig
||Lot dependent; please refer to CoA along with shipment
||WB: 1-3 µg/ml.
|Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.|
|Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
|Homo sapiens activating transcription factor 4 (ATF4), transcript variant 1|
|CREB-2; CREB2; TAXREB67; TXREB|
Entrez Gene 468 Human
Entrez Gene 11911 Mouse
Entrez Gene 79255 Rat
|This gene encodes a transcription factor that was originally identified as a widely expressed mammalian DNA binding protein that could bind a tax-responsive enhancer element in the LTR of HTLV-1. The encoded protein was also isolated and characterized as the cAMP-response element binding protein 2 (CREB-2). The protein encoded by this gene belongs to a family of DNA-binding proteins that includes the AP-1 family of transcription factors, cAMP-response element binding proteins (CREBs) and CREB-like proteins. These transcription factors share a leucine zipper region that is involved in protein-protein interactions, located C-terminal to a stretch of basic amino acids that functions as a DNA binding domain. Two alternative transcripts encoding the same protein have been described. Two pseudogenes are located on the X chromsome at q28 in a region containing a large inverted duplication. [provided by RefSeq]. |
|Transcription Factors MAPK signaling pathwayLong-term potentiationNeurotrophin signaling pathwayGnRH signaling pathwayProstate cancer|
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TA302638 staining (1µg/ml) of Raji lysate (RIPA buffer, 35µg total protein per lane). Primary incubated for 1 hour. Detected by western blot using chemiluminescence.