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Home Antibody All anti-SOCS3 antibodies

Anti-SOCS3 Antibody

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA302617
  • Goat Polyclonal Antibody against SOCS3
  • FREE positive control: HEK293T cell transient overexpression lysate (LC401300) , 20ug
100ug $325 In Stock
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WB(1)
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Also for SOCS3 (NM_003955)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenPeptide with sequence C-PIREFLDQYDAPL, from the C Terminus of the protein sequence according to NP_003946.3.
Clone Name IsotypeGoat IgG
Species ReactivityHuman, Mouse, Rat, Dog, porcine Concentration0.5 mg/ml
Guaranteed Application *WB Suggested DilutionsWB: 4-6µg/ml.
BufferSupplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Purification Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.

Reference Data

Target NameHomo sapiens suppressor of cytokine signaling 3 (SOCS3)
Alternative NameATOD4; CIS3; Cish3; SOCS-3; SSI-3; SSI3
Database LinkNP_003946
FunctionThis gene encodes a member of the STAT-induced STAT inhibitor (SSI), also known as suppressor of cytokine signaling (SOCS), family. SSI family members are cytokine-inducible negative regulators of cytokine signaling. The expression of this gene is induced by various cytokines, including IL6, IL10, and interferon (IFN)-gamma. The protein encoded by this gene can bind to JAK2 kinase, and inhibit the activity of JAK2 kinase. Studies of the mouse counterpart of this gene suggested the roles of this gene in the negative regulation of fetal liver hematopoiesis, and placental development. [provided by RefSeq].
Related Pathway
Adipogenesis
EGFR1 Signaling Pathway
Jak-STAT signaling pathway

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WB Image
TA302617 staining (5µg/ml) of MOLT-4 lysate (RIPA buffer, 30µg total protein per lane). Primary incubated for 1 hour. Detected by western blot using chemiluminescence.

 

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