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Home Antibody All anti-SDHB antibodies

Anti-SDHB Antibody


Specifications Citations Customer Reviews Product Documents
SKU Description Amount Price Availability*  
TA302600 Goat Polyclonal Antibody against SDHB 100ug $325 3-7 Days
LC401052 SDHB HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
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OriGene Data

ImmunogenPeptide with sequence C-ATYKEKKASV, from the C Terminus of the protein sequence according to NP_002991.1.
Clone Name IsotypeGoat IgG
Species ReactivityTest: Human. Expected from seq similarity: Human Concentration0.5 mg/ml
Guaranteed Application *WB Suggested DilutionsELISA: 1:8,000. WB: 0.03-0.1µg/ml.
Predicted MW Explanation 35254Da
BufferSupplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Purification Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.

Reference Data

Target NameHomo sapiens succinate dehydrogenase complex, subunit B, iron sulfur (Ip) (SDHB)
Alternative NameCWS2; IP; PGL4; SDH; SDH1; SDH2; SDHIP
Database LinkNP_002991
Entrez Gene 6390 Human
FunctionComplex II of the respiratory chain, which is specifically involved in the oxidation of succinate, carries electrons from FADH to CoQ. The complex is composed of four nuclear-encoded subunits and is localized in the mitochondrial inner membrane. The iron-sulfur subunit is highly conserved and contains three cysteine-rich clusters which may comprise the iron-sulfur centers of the enzyme. Sporadic and familial mutations in this gene result in paragangliomas and pheochromocytoma, and support a link between mitochondrial dysfunction and tumorigenesis. [provided by RefSeq].
Related PathwayDruggable Genome Citrate cycle (TCA cycle)Oxidative phosphorylationMetabolic pathwaysAlzheimer's diseaseParkinson's diseaseHuntington's diseaseMore Pathways >>

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
TA302600 (0.03µg/ml) staining of Human Liver lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.


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