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Home Antibody All anti-PC antibodies

Anti-PC Antibody

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA302584
  • Goat Polyclonal Antibody against Pyruvate Carboxylase
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC400340) , 20ug
100ug 325 3-7 Days
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WB(1)
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Also for PC (NM_000920)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenPeptide with sequence C-KFKEVKKAYVEANQ, from the internal region of the protein sequence according to NP_000911.2; NP_001035806.1; NP_071504.2.
Clone Name IsotypeGoat IgG
Species ReactivityTest: Mouse. Expected from seq similarity: Human, Mouse, Rat, Dog, Cow, Pig Concentration0.5 mg/ml
Guaranteed Application *WB Suggested DilutionsELISA: 1:16,000. WB: 0.03-0.1µg/ml.
BufferSupplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Purification Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.

Reference Data

Target NameHomo sapiens pyruvate carboxylase (PC), transcript variant 1
Alternative NamePCB
Database LinkNP_000911
FunctionThis gene encodes pyruvate carboxylase, which requires biotin and ATP to catalyse the carboxylation of pyruvate to oxaloacetate. The active enzyme is a homotetramer arranged in a tetrahedron which is located exclusively in the mitochondrial matrix. Pyruvate carboxylase is involved in gluconeogenesis, lipogenesis, insulin secretion and synthesis of the neurotransmitter glutamate. Mutations in this gene have been associated with pyruvate carboxylase deficiency. Alternatively spliced transcript variants with different 5' UTRs, but encoding the same protein, have been found for this gene. [provided by RefSeq].
Related Pathway

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WB Image
TA302584 (0.03µg/ml) staining of Mouse Liver lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

 

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