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Home Antibody All anti-PDE4B antibodies

Anti-PDE4B Antibody


Specifications Citations Customer Reviews Product Documents
SKU Description Amount Price Availability*  
TA302571 Goat Polyclonal Antibody against Phosphodiesterase 4B 100ug $325 3-7 Days
LC400919 PDE4B HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
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OriGene Data

ImmunogenPeptide with sequence C-DIDIATEDKSPVDT, from the C Terminus of the protein sequence according to NP_002591.2; NP_001032418.1; NP_001032416.1; NP_001032417.1.
Clone Name IsotypeGoat IgG
Species ReactivityTest: Mouse. Expected from seq similarity: Human, Mouse, Rat Concentration0.5 mg/ml
Guaranteed Application *WB Suggested DilutionsELISA: 1:8,000. WB: 0.5-1.0 µg/ml.
Predicted MW Explanation 86975Da
BufferSupplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Purification Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.

Reference Data

Target NameHomo sapiens phosphodiesterase 4B, cAMP-specific (PDE4B), transcript variant a
Alternative NameDPDE4; PDE4B5; PDEIVB
Database LinkNP_002591
Entrez Gene 5142 Human
Entrez Gene 18578 Mouse
Entrez Gene 24626 Rat
FunctionThis gene is a member of the type IV, cyclic AMP (cAMP)-specific, cyclic nucleotide phosphodiesterase (PDE) family. Cyclic nucleotides are important second messengers that regulate and mediate a number of cellular responses to extracellular signals, such as hormones, light, and neurotransmitters. The cyclic nucleotide phosphodiesterases (PDEs) regulate the cellular concentrations of cyclic nucleotides and thereby play a role in signal transduction. This gene encodes a protein that specifically hydrolyzes cAMP. Altered activity of this protein has been associated with schizophrenia and bipolar affective disorder. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq].
Related PathwayDruggable Genome Purine metabolismProgesterone-mediated oocyte maturation

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
TA302571 (0.5µg/ml) staining of Mouse Brain Lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.


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