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Home Antibody All anti-SH2B3 antibodies

Anti-SH2B3 Antibody

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA302531
  • Goat Polyclonal Antibody against LNK / SH2B3
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC401678) , 20ug Explanation
100ug 325 3-7 Days
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WB(1)
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Also for SH2B3 (NM_005475)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenPeptide with sequence NGPALQPSSPC, from the N Terminus of the protein sequence according to NP_005466.1.
Clone Name IsotypeGoat IgG
Species ReactivityTest: Human. Expected from seq similarity: Human Concentration0.5 mg/ml
Guaranteed Application *WB Suggested DilutionsELISA: 1:64,000. WB: 0.3-1.0 µg/ml.
Predicted MW Explanation 66854Da
BufferSupplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Purification Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.

Reference Data

Target NameHomo sapiens SH2B adaptor protein 3 (SH2B3), transcript variant 1
Alternative NameIDDM20; LNK
Database LinkNP_005466
Entrez Gene 10019 Human
FunctionT-cell activation requires stimulation of the T-cell receptor (TCR; see MIM 186880)-CD3 (see CD3Z; MIM 186780) complex, followed by recruitment of an array of intracellular signaling proteins (e.g., GRB2 (MIM 108355) and PLCG1 (MIM 172420)). Mediating the interaction between the extracellular receptors and intracellular signaling pathways are adaptor proteins such as LAT (MIM 602354), TRIM (MIM 604962), and LNK.[supplied by OMIM].
Related Pathway Neurotrophin signaling pathway

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
TA302531 (0.3µg/ml) staining of MOLT4 lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

 

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