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Home Antibody All anti-HSD11B1 antibodies

Anti-HSD11B1 Antibody

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA302508
  • Goat Polyclonal Antibody against HSD11B1 / HDL
  • FREE positive control: HEK293T cell transient overexpression lysate (LC401695) , 20ug
100ug 325 3-7 Days
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WB(1)
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Also for HSD11B1 (NM_005525)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenPeptide with sequence CTSYNMDRFINK, from the C Terminus of the protein sequence according to NP_005516.1; NP_861420.1.
Clone Name IsotypeGoat IgG
Species ReactivityHuman, Chimpanzee, Sheep, Cow Concentration0.5 mg/ml
Guaranteed Application *WB Suggested DilutionsELISA: 1:4,000. WB: 0.3-2µg/ml.
BufferSupplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Purification Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.

Reference Data

Target NameHomo sapiens hydroxysteroid (11-beta) dehydrogenase 1 (HSD11B1), transcript variant 1
Alternative Name11-beta-HSD1; 11-DH; CORTRD2; HDL; HSD11; HSD11B; HSD11L; SDR26C1
Database LinkNP_005516
FunctionThe protein encoded by this gene is a microsomal enzyme that catalyzes the conversion of the stress hormone cortisol to the inactive metabolite cortisone. In addition, the encoded protein can catalyze the reverse reaction, the conversion of cortisone to cortisol. Too much cortisol can lead to central obesity, and a particular variation in this gene has been associated with obesity and insulin resistance in children. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq].
Related Pathway

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WB Image
TA302508 (0.3µg/ml) staining of Human Liver lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

 

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