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Home Antibody All anti-GNRHR antibodies

Anti-GNRHR Antibody

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA302503
  • Goat Polyclonal Antibody against GRHR / LRHR
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC400144) , 20ug
100ug 325 3-7 Days
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WB(1)

OriGene Data

ImmunogenPeptide with sequence C-QKWTQKKEKGK, from the internal region of the protein sequence according to NP_000397.1; NP_001012781.1.
Clone Name IsotypeGoat IgG
Species ReactivityHuman, Dog Concentration0.5 mg/ml
Guaranteed Application *WB Suggested DilutionsELISA: 1:32,000. WB: 0.5-1.5µg/ml.
BufferSupplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Purification Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.

Reference Data

Target NameHomo sapiens gonadotropin-releasing hormone receptor (GNRHR), transcript variant 1
Alternative NameGNRHR1; GRHR; HH7; LHRHR; LRHR
Database LinkNP_000397
FunctionThis gene encodes the receptor for type 1 gonadotropin-releasing hormone. This receptor is a member of the seven-transmembrane, G-protein coupled receptor (GPCR) family. It is expressed on the surface of pituitary gonadotrope cells as well as lymphocytes, breast, ovary, and prostate. Following binding of gonadotropin-releasing hormone, the receptor associates with G-proteins that activate a phosphatidylinositol-calcium second messenger system. Activation of the receptor ultimately causes the release of gonadotropic luteinizing hormone (LH) and follicle stimulating hormone (FSH). Defects in this gene are a cause of hypogonadotropic hypogonadism (HH). Alternative splicing results in multiple transcript variants encoding different isoforms. More than 18 transcription initiation sites in the 5' region and multiple polyA signals in the 3' region have been identified for this gene. [provided by RefSeq].
Related Pathway
Signaling by GPCR

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WB Image
TA302503 (0.5µg/ml) staining of Human Peripheral Blood Mononucleocyte lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

 

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