Home Antibody All anti-FGR antibodies
|Peptide with sequence C-TSAEPQYQPGDQT, from the C Terminus of the protein sequence according to NP_005239.|
|Test: Mouse. Expected from seq similarity: Human, Mouse, Rat, Dog
|Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.|
|Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
|Homo sapiens FGR proto-oncogene, Src family tyrosine kinase (FGR), transcript variant 1|
|c-fgr; c-src2; p55-Fgr; p55c-fgr; p58-Fgr; p58c-fgr; SRC2|
Entrez Gene 2268 Human
Entrez Gene 14191 Mouse
Entrez Gene 79113 Rat
Entrez Gene 487341 Dog
|This gene is a member of the Src family of protein tyrosine kinases (PTKs). The encoded protein contains N-terminal sites for myristylation and palmitylation, a PTK domain, and SH2 and SH3 domains which are involved in mediating protein-protein interactions with phosphotyrosine-containing and proline-rich motifs, respectively. The protein localizes to plasma membrane ruffles, and functions as a negative regulator of cell migration and adhesion triggered by the beta-2 integrin signal transduction pathway. Infection with Epstein-Barr virus results in the overexpression of this gene. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq]. |
|Protein KinaseDruggable Genome Chemokine signaling pathway|
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TA302485 staining (0.5µg/ml) of Mouse Spleen extracts (RIPA buffer, 35µg total protein per lane). Primary incubated for 1 hour. Detected by western blot using chemiluminescence.