Home Antibody All anti-PTGER4 antibodies
Also for PTGER4 (NM_000958)
|Peptide with sequence C-LEREVSKNPDLQA, from the internal region of the protein sequence according to NP_000949.1.|
|Test: Human. Expected from seq similarity: Human, Dog
||ELISA: 1:16,000. WB: 0.1-0.3µg/ml.
|Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.|
|Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
|Homo sapiens prostaglandin E receptor 4 (subtype EP4) (PTGER4)|
Entrez Gene 5734 Human
Entrez Gene 403589 Dog
|The protein encoded by this gene is a member of the G-protein coupled receptor family. This protein is one of four receptors identified for prostaglandin E2 (PGE2). This receptor can activate T-cell factor signaling. It has been shown to mediate PGE2 induced expression of early growth response 1 (EGR1), regulate the level and stability of cyclooxygenase-2 mRNA, and lead to the phosphorylation of glycogen synthase kinase-3. Knockout studies in mice suggest that this receptor may be involved in the neonatal adaptation of circulatory system, osteoporosis, as well as initiation of skin immune responses. [provided by RefSeq]. |
|GPCRTransmembraneDruggable Genome Neuroactive ligand-receptor interaction|
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TA302476 (0.1µg/ml) staining of Human Testes lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.