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Home Antibody All anti-DKK1 antibodies

Anti-DKK1 Antibody

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Specifications Citations (0) Related Products Product Documents
SKU Description Amount Price Availability*  
TA302464 Goat Polyclonal Antibody against DKK1 100ug $325 In Stock
LC402176 DKK1 HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
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WB(1)

OriGene Data

ImmunogenPeptide with sequence CDHHQASNSSRLHT, from the C Terminus of the protein sequence according to NP_036374.
Clone Name IsotypeGoat IgG
Species ReactivityTest: Human. Expected from seq similarity: Human, Rat, Dog, Pig, Cow ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB Suggested DilutionsELISA: 1:128,000. WB: 1-3µg/ml.
Predicted MW Explanation 32296Da
BufferSupplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Purification Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.

Reference Data

Target NameHomo sapiens dickkopf WNT signaling pathway inhibitor 1 (DKK1)
Alternative NameDKK-1; SK
Database LinkNP_036374
Entrez Gene 22943 Human
Entrez Gene 293897 Rat
Entrez Gene 609600 Dog
FunctionThis gene encodes a protein that is a member of the dickkopf family. It is a secreted protein with two cysteine rich regions and is involved in embryonic development through its inhibition of the WNT signaling pathway. Elevated levels of DKK1 in bone marrow plasma and peripheral blood is associated with the presence of osteolytic bone lesions in patients with multiple myeloma. [provided by RefSeq].
Related PathwayStem cell relevant signaling - Wnt Signaling pathwaySecreted ProteinES Cell Differentiation/IPSAdult stem cellsCancer stem cellsDruggable Genome Wnt signaling pathway

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

TA302464 (1µg/ml) staining of human bone marrow lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
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