Home Antibody All anti-DISC1 antibodies
Also for DISC1 (NM_018662)
|Peptide with sequence C-HSEDKRKTPLKVLE, from the internal region of the protein sequence according to NP_001012975.1; NP_061132.2.|
|Test: Human. Expected from seq similarity: Human
||ELISA: 1:128,000. WB: 0.1-0.3µg/ml.
|Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.|
|Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
|Homo sapiens disrupted in schizophrenia 1 (DISC1), transcript variant L|
Entrez Gene 27185 Human
|This gene encodes a protein with multiple coiled coil motifs which is located in the nucleus, cytoplasm and mitochondria. The protein is involved in neurite outgrowth and cortical development through its interaction with other proteins. This gene is disrupted in a t(1;11)(q42.1;q14.3) translocation which segregates with schizophrenia and related psychiatric disorders in a large Scottish family. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq]. |
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TA302463 (0.1µg/ml) staining of human brain (hippocampus) lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.