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Home Antibody All anti-CHRM1 antibodies

Anti-CHRM1 Antibody


Specifications Citations Customer Reviews Product Documents
SKU Description Amount Price Availability*  
TA302450 Goat Polyclonal Antibody against Cholinergic receptor / CHRM1 100ug $325 In Stock
LC400263 CHRM1 HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
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OriGene Data

ImmunogenPeptide with sequence C-DKRRWRKIPKRPGSVH, from the C Terminus of the protein sequence according to NP_000729.2.
Clone Name IsotypeGoat IgG
Species ReactivityTest: Human. Expected from seq similarity: Human, Mouse, Rat, Dog ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB Suggested DilutionsELISA: 1:16,000. WB: 1-3µg/ml.
Predicted MW Explanation 55048Da
BufferSupplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Purification Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.

Reference Data

Target NameHomo sapiens cholinergic receptor, muscarinic 1 (CHRM1)
Alternative NameHM1; M1; M1R
Database LinkNP_000729
Entrez Gene 1128 Human
Entrez Gene 12669 Mouse
Entrez Gene 25229 Rat
Entrez Gene 483776 Dog
FunctionThe muscarinic cholinergic receptors belong to a larger family of G protein-coupled receptors. The functional diversity of these receptors is defined by the binding of acetylcholine and includes cellular responses such as adenylate cyclase inhibition, phosphoinositide degeneration, and potassium channel mediation. Muscarinic receptors influence many effects of acetylcholine in the central and peripheral nervous system. The muscarinic cholinergic receptor 1 is involved in mediation of vagally-induced bronchoconstriction and in the acid secretion of the gastrointestinal tract. The gene encoding this receptor is localized to 11q13. [provided by RefSeq].
Related PathwayGPCRTransmembraneDruggable Genome Calcium signaling pathwayNeuroactive ligand-receptor interactionRegulation of actin cytoskeleton

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
TA302450 (1µg/ml) staining of Human Brain lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.


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