Home Antibody All anti-CNR1 antibodies
Also for CNR1 (NM_033181)
|Peptide with sequence C-HTSEDGKVQVTRPDQ, from the internal region of the protein sequence according to NP_057167.2; NP_149421.1.|
|Test: Human, Mouse. Expected from seq similarity: Human, Mouse, Rat, Dog
||ELISA: 1:32,000. WB: 1-3µg/ml.
|Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.|
|Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
|Homo sapiens cannabinoid receptor 1 (brain) (CNR1), transcript variant 2|
|CANN6; CB-R; CB1; CB1A; CB1K5; CB1R; CNR|
Entrez Gene 1268 Human
Entrez Gene 12801 Mouse
Entrez Gene 25248 Rat
Entrez Gene 481913 Dog
|This gene encodes a protein that is one of two cannabinoid receptors. The cannabinoids, principally delta-9-tetrahydrocannabinol and synthetic analogs, are psychoactive ingredients of marijuana. The cannabinoid receptors are members of the family of guanine-nucleotide-binding protein (G-protein) coupled receptors which inhibit adenylate cyclase activity in a dose-dependent, stereoselective and pertussis toxin-sensitive manner. The two receptors have been found to be involved in the cannabinoid-induced CNS effects (including alterations in mood and cognition) experienced by users of marijuana. Two transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq]. |
|GPCRTransmembraneDruggable Genome Neuroactive ligand-receptor interaction|
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TA302439 (1µg/ml) staining of human brain lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.