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Home Antibody All anti-SMARCE1 antibodies

Anti-SMARCE1 Antibody

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA302426
  • Goat Polyclonal Antibody against BAF57 / SMARCE1
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC401073) , 20ug Explanation
100ug 325 3-7 Days
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WB(1)
IHC(1)
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Also for SMARCE1 (NM_003079)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenPeptide with sequence C-PPTDPIPEDEKKE, from the C Terminus of the protein sequence according to NP_003070.3.
Clone Name IsotypeGoat IgG
Species ReactivityTest: Human. Expected from seq similarity: Human, Mouse Concentration0.5 mg/ml
Guaranteed Application *WB, IHC Suggested DilutionsELISA: 1:16,000. WB: 0.2-0.6µg/ml.
Predicted MW Explanation 50276Da
BufferSupplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Purification Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.

Reference Data

Target NameHomo sapiens SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1 (SMARCE1)
Alternative NameBAF57
Database LinkNP_003070
Entrez Gene 6605 Human
Entrez Gene 57376 Mouse
FunctionThe protein encoded by this gene is part of the large ATP-dependent chromatin remodeling complex SWI/SNF, which is required for transcriptional activation of genes normally repressed by chromatin. The encoded protein, either alone or when in the SWI/SNF complex, can bind to 4-way junction DNA, which is thought to mimic the topology of DNA as it enters or exits the nucleosome. The protein contains a DNA-binding HMG domain, but disruption of this domain does not abolish the DNA-binding or nucleosome-displacement activities of the SWI/SNF complex. Unlike most of the SWI/SNF complex proteins, this protein has no yeast counterpart. [provided by RefSeq].
Related PathwayTranscription Factors

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
A) HEK293 overexpressing BAF57 (RC209444) and probed with TA302426 (mock transfection in first lane), tested by Origene. B) Western blot of Jurkat cells
IHC Image
In paraffin embedded Human Prostate shows nuclear staining in secretory epithelial cells. Recommended concentration, 3-5µg/ml.

 

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