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Home Antibody All anti-PIK3CG antibodies

Anti-PIK3CG Antibody

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA302284
  • Rabbit Polyclonal Antibody against PIK3CG (Center)
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC419184) , 20ug Explanation
100ug 325 In Stock
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WB(1)
IHC(1)
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Also for PIK3CG (NM_002649)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenThis PI3KCG antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 518-547 amino acids from the Central region of human PI3KCG.
Clone Name IsotypeRabbit Ig
Species ReactivityHuman Concentration0.25 mg/ml
Guaranteed Application *WB, IHC Suggested DilutionsWB: 1:1000, IHC: 1:10~50
Predicted MW Explanation 126454 Da
BufferPurified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.
Purification This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Reference Data

Target NameHomo sapiens phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma (PIK3CG), transcript variant 1
Alternative Namep110gamma; p120-PI3K; PI3CG; PI3K; PI3Kgamma; PIK3
Database LinkNP_002640
Entrez Gene 5294 Human
FunctionPIK3CG belongs to the pi3/pi4-kinase family of proteins. It is an enzyme that phosphorylates phosphoinositides on the 3-hydroxyl group of the inositol ring. It is an important modulator of extracellular signals, including those elicited by E-cadherin-mediated cell-cell adhesion, which plays an important role in maintenance of the structural and functional integrity of epithelia. In addition to its role in promoting assembly of adherens junctions, the protein is thought to play a pivotal role in the regulation of cytotoxicity in NK cells. The gene for this protein is located in a commonly deleted segment of chromosome 7 previously identified in myeloid leukemias.
Related PathwayES Cell Differentiation/IPSDruggable Genome Inositol phosphate metabolismErbB signaling pathwayChemokine signaling pathwayPhosphatidylinositol signaling systemmTOR signaling pathwayApoptosisMore Pathways >>

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot analysis of PI3KCG Antibody (Center) Pab (Cat.#TA302284)(arrow) using purified Pab. 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the PI3KCG gene (Lane 2) (Origene Technologies).
IHC Image
Formalin-fixed and paraffin-embedded skeletal muscle tissue reacted with PI3KCG antibody (Center)(Cat.#TA302284), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.

 

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