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Home Antibody All anti-AKT3 antibodies

Anti-AKT3 Antibody

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA302231
  • Rabbit Polyclonal Antibody against AKT3 (N-term)
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC401675) , 20ug
100ug 325 3-7 Days
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WB(1)
IHC(1)
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Also for AKT3 (NM_005465)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenThis antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the N-terminal region of human AKT3 Antibody.
Clone Name IsotypeRabbit Ig
Species ReactivityHuman Concentration0.25 mg/ml
Guaranteed Application *WB, IHC Suggested DilutionsWB: 1:50~100; IHC: 1:50-100; ELISA: 1: 1,000;
BufferPurified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.
Purification Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.

Reference Data

Target NameHomo sapiens v-akt murine thymoma viral oncogene homolog 3 (AKT3), transcript variant 1
Alternative NameMPPH; MPPH2; PKB-GAMMA; PKBG; PRKBG; RAC-gamma; RAC-PK-gamma; STK-2
Database LinkNP_005456
FunctionAKT3 is a member of the AKT, also called PKB, serine/threonine protein kinase family. AKT kinases are known to be regulators of cell signaling in response to insulin and growth factors. They are involved in a wide variety of biological processes including cell proliferation, differentiation, apoptosis, tumorigenesis, as well as glycogen synthesis and glucose uptake. This kinase has been shown to be stimulated by platelet-derived growth factor (PDGF), insulin, and insulin-like growth factor 1 (IGF1).
Related Pathway
Focal Adhesion
Hemostasis
Jak-STAT signaling pathway
MAPK signaling pathway
Signaling by GPCR
Toll-like receptor signaling pathway

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
(LEFT)Western blot analysis of anti-AKT3 Antibody (N-term) Pab in Hela cell line lysates (35ug/lane). AKT3(arrow) was detected using the purified Pab (1:30 dilution). (RIGHT)Western blot analysis of anti-AKT3 Antibody (N-term) Pab in 293 cell line lysates transiently transfected with the AKT3 gene (2ug/lane). AKT3(arrow) was detected using the purified Pab (1:60 dilution).
IHC Image
Formalin-fixed and paraffin-embedded human breast carcinoma reacted with AKT3 Antibody (N-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.

 

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