Home Antibody All anti-AK3L1 antibodies
Also for AK3L1 (NM_013410)
|This AK3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 195-223 amino acids from the C-terminal region of human AK3.|
|Human, Mouse (Predicted: Rat)
||WB: 1:1000, IHC: 1:50~100
|Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.|
|This antibody is purified through a protein A column, followed by peptide affinity purification.
|Homo sapiens adenylate kinase 4 (AK4), transcript variant 2|
|AK 4; AK3; AK3L1; AK3L2|
Entrez Gene 205 Human
Entrez Gene 11639 Mouse
Entrez Gene 29223 Rat
|AK3 is a member of the adenylate kinase family of enzymes. The encoded protein is localized to the mitochondrial matrix. Adenylate kinases regulate the adenine and guanine nucleotide compositions within a cell by catalyzing the reversible transfer of phosphate group among these nucleotides. Five isozymes of adenylate kinase have been identified in vertebrates. Expression of these isozymes is tissue-specific and developmentally regulated.|
|Druggable Genome Purine metabolismMetabolic pathways|
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The anti-AK3 Pab (Cat. #TA302218) is used in Western blot to detect AK3 in mouse kidney tissue lysate.
Western blot analysis of AK3 (arrow) using rabbit polyclonal AK3 Antibody (C-term H38) (Cat. #TA302218). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the AK3 gene (Lane 2) (Origene Technologies).
Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma.