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Home Antibody All anti-RPS6KB1 antibodies

Anti-RPS6KB1 Antibody

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA302199
  • Rabbit Polyclonal Antibody against RPS6KB1 (Center)
  • FREE positive control: HEK293T cell transient overexpression lysate (LC401097) , 20ug
100ug 325 In Stock
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WB(1)
IHC(1)
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Also for RPS6KB1 (NM_003161)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenThis antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the center region of human RPS6KB1.
Clone Name IsotypeRabbit Ig
Species ReactivityHuman Concentration0.25 mg/ml
Guaranteed Application *WB, IHC Suggested DilutionsWB: 1:50~100; IHC: 1:50-100; ELISA: 1: 1,000;
BufferPurified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.
Purification This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Reference Data

Target NameHomo sapiens ribosomal protein S6 kinase, 70kDa, polypeptide 1 (RPS6KB1), transcript variant 1
Alternative Namep70 S6KA; p70(S6K)-alpha; p70-alpha; p70-S6K; PS6K; S6K; S6K-beta-1; S6K1; STK14A
Database LinkNP_003152
FunctionThis gene encodes a member of the RSK (ribosomal S6 kinase) family of serine/threonine kinases. This kinase contains 2 non-identical kinase catalytic domains and phosphorylates several residues of the S6 ribosomal protein. The kinase activity of this protein leads to an increase in protein synthesis and cell proliferation. Amplification of the region of DNA encoding the gene for RPS6KB1 and overexpression of this kinase are seen in some breast cancer cell lines.
Related Pathway
TGF Beta Signaling Pathway

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WB Image
(LEFT) Western blot analysis of anti-RPS6KB1 Antibody (Center) Pab in Jurkat and 293 cell line lysates. RPS6KB1(arrow) was detected using the purified Pab. (RIGHT)Western blot analysis of anti-RPS6KB1 Antibody (Center) Pab in 293 cell line lysates transiently transfected with the RPS6KB1 gene (2ug/lane). RPS6KB1(arrow) was detected using the purified Pab (1:60 dilution).
IHC Image
Formalin-fixed and paraffin-embedded human breast carcinoma reacted with RPS6KB1 Antibody (Center), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.

 

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