Homo sapiens KIT ligand (KITLG), transcript variant b
Synonyms:
FPH2; Kitl; KL-1; MGF; SCF; SF; SHEP7
Immunogen
This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the N-terminal region of human KITLG.
Buffer
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.
Clone Name
Isotype
Rabbit Ig
Species Reactivity
Human
Concentration
0.25 mg/ml
Purification
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS. (Protein A or G Sepharose)
Guaranteed Application *
WB, IHC
Suggested Dilutions
WB: 1:50~100; IHC: 1: 10~50; ELISA: 1: 1,000;
Background
KITLG is the ligand of the tyrosine-kinase receptor encoded by the KIT locus. This ligand is a pleiotropic factor that acts in utero in germ cell and neural cell development, and hematopoiesis, all believed to reflect a role in cell migration. In adults, it functions pleiotropically, while mostly noted for its continued requirement in hematopoiesis.
Related Pathway
Cytokine-cytokine receptor interaction
Hematopoietic cell lineage
Melanogenesis
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* OriGene provides validated application data and protocol, with money back guarantee.
Western blot analysis of KITLG (arrow) using rabbit polyclonal KITLG Antibody (N-term) .293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the KITLG gene (Lane 2) (Origene Technologies).
Formalin-fixed and paraffin-embedded human colon carcinoma tissue reacted with KITLG antibody (N-term) , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
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