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Home Antibody All anti-CD8A antibodies

Anti-CD8A Antibody

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA302179
  • Rabbit Polyclonal Antibody against CD8A (C-term)
  • FREE positive control: HEK293T cell transient overexpression lysate (LC403530) , 20ug
100ug $325 3-7 Days
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WB(1)
IHC(1)
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Also for CD8A (NM_171827)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenThis antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the C-terminal region of human CD8A.
Clone Name IsotypeRabbit Ig
Species ReactivityHuman Concentration0.25 mg/ml
Guaranteed Application *WB, IHC Suggested DilutionsWB: 1:50~100; IHC: 1: 10~50; ELISA: 1: 1,000;
BufferPurified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.

Reference Data

Target NameHomo sapiens CD8a molecule (CD8A), transcript variant 2
Alternative NameCD8; Leu2; MAL; p32
Database LinkNP_741969
FunctionThe CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system. The CD8 antigen, acting as a co-receptor, and the T-cell receptor on the T lymphocyte recognize antigen displayed by an antigen presenting cell (APC) in the context of class I MHC molecules. The functional co-receptor is either a homodimer composed of two alpha chains, or a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains.
Related Pathway
Hematopoietic cell lineage

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WB Image
Western blot analysis of CD8A(arrow) using rabbit polyclonal CD8A Antibody (C-term) . 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the CD8A gene (Lane 2) (Origene Technologies).
IHC Image
Formalin-fixed and paraffin-embedded human lung carcinoma tissue reacted with CD8A antibody (C-term) , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.

 

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