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Home Antibody All anti-PIK3CA antibodies

Anti-PIK3CA Antibody


Specifications Citations Customer Reviews Product Documents
SKU Description Amount Price Availability*  
TA302178 Rabbit Polyclonal Antibody against PIK3CA (Center) 100ug $325 In Stock
LC416797 PIK3CA HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
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OriGene Data

ImmunogenThis PI3KCA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 504-533 amino acids from the Central region of human PI3KCA.
Clone Name IsotypeRabbit Ig
Species ReactivityHuman Concentration0.25 mg/ml
Guaranteed Application *WB, IHC Suggested DilutionsWB: 1:1000, IHC: 1:50~100
Predicted MW Explanation 124284 Da
BufferPurified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.
Purification This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Reference Data

Target NameHomo sapiens phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha (PIK3CA)
Alternative NameCLOVE; CWS5; MCAP; MCM; MCMTC; p110-alpha; PI3K
Database LinkNP_006209
Entrez Gene 5290 Human
FunctionPhosphatidylinositol 3-kinase is composed of an 85 kDa regulatory subunit and a 110 kDa catalytic subunit. The protein encoded by this gene represents the catalytic subunit, which uses ATP to phosphorylate PtdIns, PtdIns4P and PtdIns(4,5)P2. This gene has been found to be oncogenic and has been implicated in cervical cancers.
Related PathwayDruggable Genome Inositol phosphate metabolismErbB signaling pathwayChemokine signaling pathwayPhosphatidylinositol signaling systemmTOR signaling pathwayApoptosisMore Pathways >>

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot analysis of anti-PIK3CA Antibody (Center) Pab (Cat.#TA302178) in K562 cell line lysates (35ug/lane). PIK3CA (arrow) was detected using the purified Pab

WB Image
Western blot analysis of anti-PI3KCA Antibody (Center) Pab (Cat.#TA302178) in 293 cell line lysates transiently transfected with the PIK3CA gene (1ug/lane). PI3KCA (arrow) was detected using the purified Pab.

IHC Image
Formalin-fixed and paraffin-embedded human breast carcinoma reacted with PI3KCA Antibody (Center)(Cat.#TA302178), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.


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