Home Antibody All anti-CDH3 antibodies
Also for CDH3 (NM_001793)
|This CDH3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 660-688 amino acids from the C-terminal region of human CDH3.|
||Lot dependent; please refer to CoA along with shipment
|WB, ELISA, IHC
||WB: 1:1000, IHC: 1:10~50
|Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.|
|This antibody is purified through a protein A column, followed by peptide affinity purification.
|Homo sapiens cadherin 3, type 1, P-cadherin (placental) (CDH3)|
|CDHP; HJMD; PCAD|
Entrez Gene 1001 Human
|CDH3 is a classical cadherin from the cadherin superfamily. It is a calcium-dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Aberrant expression of this protein is observed in cervical adenocarcinomas. Mutations in the gene encoding CDH3 have been associated with congential hypotrichosis with juvenile macular dystrophy.|
|TransmembraneDruggable Genome Cell adhesion molecules (CAMs)|
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Western blot analysis of anti-CDH3 Antibody (C-term) (Cat.#TA302124) in K562 cell line lysates (35ug/lane). CDH3(arrow) was detected using the purified Pab.
Figure from citation: Western Blot of CDH3 protein level by using anti-CDH3 antibody in CRC patient sera. View Citation
Figure from citation: ELISA of CDH3 protein level by using anti-CDH3 antibody in CRC patient sera. Humanhttp://www.ncbi.nlm.nih.gov/pubmed/23682078Human
Formalin-fixed and paraffin-embedded human prostate carcinoma tissue reacted with CDH3 antibody (C-term) (Cat.#TA302124), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.