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Anti-CDH3 Antibody


Specifications Citations (1) Customer Reviews Product Documents
SKU Description Amount Price Availability*  
TA302124 Rabbit Polyclonal Antibody against CDH3 (C-term) 100ug $325 2 Weeks
LC400683 CDH3 HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
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OriGene Data

ImmunogenThis CDH3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 660-688 amino acids from the C-terminal region of human CDH3.
Clone Name IsotypeRabbit Ig
Species ReactivityHuman ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB, ELISA, IHC Suggested DilutionsWB: 1:1000, IHC: 1:10~50
Predicted MW Explanation 91418 Da
BufferPurified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.

Reference Data

Target NameHomo sapiens cadherin 3 (CDH3), transcript variant 1
Alternative NameCDHP; HJMD; PCAD
Database LinkNP_001784
Entrez Gene 1001 Human
FunctionCDH3 is a classical cadherin from the cadherin superfamily. It is a calcium-dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Aberrant expression of this protein is observed in cervical adenocarcinomas. Mutations in the gene encoding CDH3 have been associated with congential hypotrichosis with juvenile macular dystrophy.
Related PathwayTransmembraneDruggable Genome Cell adhesion molecules (CAMs)

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot analysis of anti-CDH3 Antibody (C-term) (Cat.#TA302124) in K562 cell line lysates (35ug/lane). CDH3(arrow) was detected using the purified Pab.

WB Image
Figure from citation: Western Blot of CDH3 protein level by using anti-CDH3 antibody in CRC patient sera. View Citation

Figure from citation: ELISA of CDH3 protein level by using anti-CDH3 antibody in CRC patient sera. Humanhttp://www.ncbi.nlm.nih.gov/pubmed/23682078Human

IHC Image
Formalin-fixed and paraffin-embedded human prostate carcinoma tissue reacted with CDH3 antibody (C-term) (Cat.#TA302124), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.


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