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Also for GUCY1A3 (NM_000856)
|This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the N-terminal region of human GUCY1A3.|
||Lot dependent; please refer to CoA along with shipment
||WB: 1: 100~500; IHC: 1:50~100; ELISA: 1: 1,000;
|Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.|
|This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
|Homo sapiens guanylate cyclase 1, soluble, alpha 3 (GUCY1A3), transcript variant 1|
|GC-SA3; GUC1A3; GUCA3; GUCSA3; GUCY1A1; MYMY6|
|Soluble guanylate cyclase (sGC), a heterodimeric protein consisting of an alpha and a beta subunit, catalyzes the conversion of GTP to the second messenger cGMP and functions as the main receptor for nitric oxide and nitrovasodilator drugs.|
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(LEFT)Western blot analysis of anti-GUCY1A3 Pab in mouse brain tissue lysate (35ug/lane). GUCY1A3(arrow) was detected using the purified Pab (1:40 dilution). (RIGHT)Western blot analysis of GUCY1A3 (arrow) using GUCY1A3 Antibody (N-term) . 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the GUCY1A3 gene (Lane 2) (Origene Technologies).
Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma.