This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide corresponding to amino acid residues surrounding Y204 of human MAPK3.
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.
Purified rabbit polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is first purified by protein A affinity chromatography, followed by peptide affinity purification in a 2-step procedure with the control and phosphorylated peptides. (Protein A or G Sepharose)
Guaranteed Application *
WB: 1:50~100; ELISA: 1: 1,000;
MAPK3 is a member of the MAP kinase family. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act in a signaling cascade that regulates various cellular processes such as proliferation, differentiation, and cell cycle progression in response to a variety of extracellular signals. This kinase is activated by upstream kinases, resulting in its translocation to the nucleus where it phosphorylates nuclear targets.
Delta-Notch Signaling Pathway
EGFR1 Signaling Pathway
MAPK signaling pathway
TGF Beta Signaling Pathway
Toll-like receptor signaling pathway
Wnt Signaling Pathway
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Western blot analysis of MAPK3 (arrow) using rabbit polyclonal MAPK3 Antibody (Y204) . 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the MAPK3 gene (Lane 2) (Origene Technologies).
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