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Home Antibody All anti-MYC antibodies

Anti-MYC Antibody

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA302044
  • Rabbit Polyclonal Antibody against MYC (S62)
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC400876) , 20ug Explanation
100ug 325 3-7 Days
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WB(1)
FC(1)
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Also for MYC (NM_002467)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenThis MYC antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 40-69 amino acids from human MYC.
Clone Name IsotypeRabbit Ig
Species ReactivityHuman (Predicted: Mouse, Rat, Bovine, Pig) Concentration0.25 mg/ml
Guaranteed Application *WB, FC Suggested DilutionsWB: 1:1000, FC: 1:10~50
Predicted MW Explanation 48804 Da
BufferPurified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.

Reference Data

Target NameHomo sapiens v-myc avian myelocytomatosis viral oncogene homolog (MYC)
Alternative NamebHLHe39; c-Myc; MRTL; MYCC
Database LinkNP_002458
Entrez Gene 4609 Human
Entrez Gene 17869 Mouse
Entrez Gene 24577 Rat
FunctionMYC is a multifunctional, nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. It functions as a transcription factor that regulates transcription of specific target genes. Mutations, overexpression, rearrangement and translocation of the gene encoding MYC have been associated with a variety of hematopoietic tumors, leukemias and lymphomas, including Burkitt lymphoma. There is evidence to show that alternative translation initiations from an upstream, in-frame non-AUG (CUG) and a downstream AUG start site result in the production of two isoforms with distinct N-termini. The synthesis of non-AUG initiated protein is suppressed in Burkitt's lymphomas, suggesting its importance in the normal function of this gene.
Related PathwayStem cell relevant signaling - JAK/STAT signaling pathwayStem cell relevant signaling - TGFb/BMP signaling pathwayStem cell relevant signaling - Wnt Signaling pathwayStem cell - PluripotencyEmbryonic stem cellsInduced pluripotent stem cellsTranscription FactorsDruggable Genome MAPK signaling pathwayErbB signaling pathwayCell cycleWnt signaling pathwayTGF-beta signaling pathwayJak-STAT signaling pathwayMore Pathways >>

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot analysis of MYC (arrow) using rabbit polyclonal MYC Antibody (S62) (Cat.#TA302044). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the MYC gene (Lane 2) (Origene Technologies).
FC Image
MYC-pS62 Antibody (Cat. #TA302044) flow cytometric analysis of 293 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.

 

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