Home Antibody All anti-MYC antibodies
|This MYC antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 40-69 amino acids from human MYC.|
|Human (Predicted: Mouse, Rat, Bovine, Pig)
||WB: 1:1000, FC: 1:10~50
|Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.|
|This antibody is purified through a protein A column, followed by peptide affinity purification.
|Homo sapiens v-myc avian myelocytomatosis viral oncogene homolog (MYC)|
|bHLHe39; c-Myc; MRTL; MYCC|
Entrez Gene 4609 Human
Entrez Gene 17869 Mouse
Entrez Gene 24577 Rat
|MYC is a multifunctional, nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. It functions as a transcription factor that regulates transcription of specific target genes. Mutations, overexpression, rearrangement and translocation of the gene encoding MYC have been associated with a variety of hematopoietic tumors, leukemias and lymphomas, including Burkitt lymphoma. There is evidence to show that alternative translation initiations from an upstream, in-frame non-AUG (CUG) and a downstream AUG start site result in the production of two isoforms with distinct N-termini. The synthesis of non-AUG initiated protein is suppressed in Burkitt's lymphomas, suggesting its importance in the normal function of this gene.|
EGFR1 Signaling Pathway
Jak-STAT signaling pathway
MAPK signaling pathway
TGF Beta Signaling Pathway
Wnt Signaling Pathway
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Western blot analysis of MYC (arrow) using rabbit polyclonal MYC Antibody (S62) (Cat.#TA302044). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the MYC gene (Lane 2) (Origene Technologies).
MYC-pS62 Antibody (Cat. #TA302044) flow cytometric analysis of 293 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.