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Home Antibody All anti-SOX2 antibodies

Anti-SOX2 Antibody

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA302025
  • Mouse Monoclonal Antibody against SOX2
  • FREE positive control: HEK293T cell transient overexpression lysate (LC401083) , 20ug
100ug 325 In Stock
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WB(1)
IHC(1)
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Also for SOX2 (NM_003106)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenSOX2 recombinant protein is used to produce this monoclonal antibody.
Clone Name IsotypeIgG1 Kappa
Species ReactivityHuman Concentration0.5~1.0 mg/ml (Lot Dependent)
Guaranteed Application *WB, IHC Suggested DilutionsWB: 1:200~2000; IHC: 1:50~100; ELISA: 1: 1,0000;
BufferPurified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.
Purification This antibody is purified through a protein G column, followed by dialysis against PBS.

Reference Data

Target NameHomo sapiens SRY (sex determining region Y)-box 2 (SOX2)
Alternative NameANOP3; MCOPS3
Database LinkNP_003097
FunctionSOX2 is a member of the SRY-related HMG-box (SOX) family of transcription factors involved in the regulation of embryonic development and in the determination of cell fate. This protein may act as a transcriptional activator after forming a protein complex with other proteins. Mutations in the SOX2 gene have been associated with bilateral anophthalmia, a severe form of structural eye malformation.
Related Pathway
Wnt Signaling Pathway

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* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
(LEFT)Western blot analysis of anti-SOX2 Monoclonal Antibody by SOX2 recombinant protein. SOX2(arrow) was detected using the purified Mab. (RIGHT)Western blot analysis of SOX2 (arrow) using mouse monoclonal SOX2 antibody . 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the SOX2 gene (Lane 2) (Origene Technologies)
IHC Image
Formalin-fixed and paraffin-embedded human lung carcinoma tissue reacted with SOX2 Monoclonal Antibody , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.

 

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