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Home Antibody All anti-ALDH2 antibodies

Anti-ALDH2 Antibody

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA302016
  • Rabbit Polyclonal Antibody against ALDH2 (Center)
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC400231) , 20ug Explanation
100ug 325 In Stock
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WB(1)
IHC(1)
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Also for ALDH2 (NM_000690)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenThis ALDH2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 318-347 amino acids from the Central region of human ALDH2.
Clone Name IsotypeRabbit Ig
Species ReactivityHuman (Predicted: Mouse, Rat) ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB, IHC Suggested DilutionsWB: 1:1000, IHC: 1:10~50
Predicted MW Explanation 56381 Da
BufferPurified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.

Reference Data

Target NameHomo sapiens aldehyde dehydrogenase 2 family (mitochondrial) (ALDH2), transcript variant 1
Alternative NameALDH-E2; ALDHI; ALDM
Database LinkNP_000681
Entrez Gene 217 Human
Entrez Gene 11669 Mouse
Entrez Gene 29539 Rat
FunctionALDH2 belongs to the aldehyde dehydrogenase family of proteins. Aldehyde dehydrogenase is the second enzyme of the major oxidative pathway of alcohol metabolism. Two major liver isoforms of this enzyme, cytosolic and mitochondrial, can be distinguished by their electrophoretic mobilities, kinetic properties, and subcellular localizations. Most Caucasians have two major isozymes, while approximately 50% of Asians have only the cytosolic isozyme, missing the mitochondrial isozyme. A remarkably higher frequency of acute alcohol intoxication among Asians than among Caucasians could be related to the absence of the mitochondrial isozyme.
Related PathwayDruggable Genome Glycolysis / GluconeogenesisAscorbate and aldarate metabolismFatty acid metabolismValine, leucine and isoleucine degradationLysine degradationArginine and proline metabolismMore Pathways >>

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
ALDH2 Antibody (Center) (Cat.# TA302016) western blot analysis in A549 cell line,mouse liver and lung,rat liver lysates (35ug/lane).This demonstrates the ALDH2 antibody detected the ALDH2 protein (arrow).
IHC Image
Formalin-fixed and paraffin-embedded human hepatocarcinoma tissue reacted with ALDH2 antibody (Center) (Cat.#TA302016), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.

 

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