Home Antibody All anti-CDC2 antibodies
Also for CDC2 (NM_001786)
|This CDC2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 213-241 amino acids from the C-terminal region of human CDC2.|
|Human (Predicted: Mouse, Rat, Xenopus)
|Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.|
|This antibody is purified through a protein A column, followed by peptide affinity purification.
|Homo sapiens cyclin-dependent kinase 1 (CDK1), transcript variant 1|
|CDC2; CDC28A; P34CDC2|
Entrez Gene 983 Human
Entrez Gene 12534 Mouse
Entrez Gene 54237 Rat
|CDC2 is a member of the Ser/Thr protein kinase family. This protein is a catalytic subunit of the highly conserved protein kinase complex known as M-phase promoting factor (MPF), which is essential for G1/S and G2/M phase transitions of eukaryotic cell cycle. Mitotic cyclins stably associate with this protein and function as regulatory subunits. The kinase activity of CDC2 is controlled by cyclin accumulation and destruction through the cell cycle. The phosphorylation and dephosphorylation of this protein also play important regulatory roles in cell cycle control.|
Hedgehog signaling pathway
TGF Beta Signaling Pathway
Wnt Signaling Pathway
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Western blot analysis of CDC2 (arrow) using rabbit polyclonal CDC2 Antibody (C-term) (Cat.#TA302014).293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the CDC2 gene (Lane 2) (Origene Technologies).