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Home Antibody All anti-CDC2 antibodies

Anti-CDC2 Antibody

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA302013
  • Rabbit Polyclonal Antibody against CDC2 (T14)
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC400676) , 20ug Explanation
100ug 325 3-7 Days
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WB(1)
IHC(1)
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Also for CDC2 (NM_001786)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenThis CDK1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from human CDK1.
Clone Name IsotypeRabbit Ig
Species ReactivityHuman (Predicted: Mouse, Rat, Bovine, Chicken, Drosophila, Xenopus) Concentration0.25 mg/ml
Guaranteed Application *WB, IHC Suggested DilutionsWB: 1:1000, IHC: 1:10~50
Predicted MW Explanation 34095 Da
BufferPurified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.

Reference Data

Target NameHomo sapiens cyclin-dependent kinase 1 (CDK1), transcript variant 1
Alternative NameCDC2; CDC28A; P34CDC2
Database LinkNP_001777
Entrez Gene 983 Human
Entrez Gene 12534 Mouse
Entrez Gene 54237 Rat
FunctionCDK1 is a member of the Ser/Thr protein kinase family. This protein is a catalytic subunit of the highly conserved protein kinase complex known as M-phase promoting factor (MPF), which is essential for G1/S and G2/M phase transitions of eukaryotic cell cycle. Mitotic cyclins stably associate with this protein and function as regulatory subunits. The kinase activity of this protein is controlled by cyclin accumulation and destruction through the cell cycle. The phosphorylation and dephosphorylation of this protein also play important regulatory roles in cell cycle control.
Related PathwayProtein KinaseStem cell - PluripotencyDruggable Genome Cell cycleOocyte meiosisp53 signaling pathwayGap junctionProgesterone-mediated oocyte maturation

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot analysis of CDK1(arrow) using rabbit polyclonal CDK1 Antibody (T14) (Cat.#TA302013). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the CDK1 gene (Lane 2) (Origene Technologies).
IHC Image
Formalin-fixed and paraffin-embedded human breast carcinoma tissue reacted with CDK1 Antibody (T14) (Cat.#TA302013), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.

 

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