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Home Antibody All anti-GRB2 antibodies

Anti-GRB2 Antibody

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA302011
  • Rabbit Polyclonal Antibody against GRB2 (Y209)
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC400765) , 20ug
100ug 325 3-7 Days
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WB(1)
IHC(1)
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Also for GRB2 (NM_002086)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenThis antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide corresponding to amino acid residues surrounding Y209 of human GRB2.
Clone Name IsotypeRabbit Ig
Species ReactivityHuman Concentration0.25 mg/ml
Guaranteed Application *WB, IHC Suggested DilutionsWB: 1:50~100; IHC: 1: 10~50; ELISA: 1: 1,000;
BufferPurified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.

Reference Data

Target NameHomo sapiens growth factor receptor-bound protein 2 (GRB2), transcript variant 1
Alternative NameASH; EGFRBP-GRB2; Grb3-3; MST084; MSTP084; NCKAP2
Database LinkNP_002077
FunctionGRB2 binds the epidermal growth factor receptor and contains one SH2 domain and two SH3 domains. Its two SH3 domains direct complex formation with proline-rich regions of other proteins, and its SH2 domain binds tyrosine phosphorylated sequences. This gene is similar to the Sem5 gene of C.elegans, which is involved in the signal transduction pathway.
Related Pathway
EGFR1 Signaling Pathway
Focal Adhesion
Hemostasis
Jak-STAT signaling pathway
MAPK signaling pathway

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot analysis of GRB2 (arrow) using rabbit polyclonal GRB2 Antibody (Y209) . 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the GRB2 gene (Lane 2) (Origene Technologies).
IHC Image
Formalin-fixed and paraffin-embedded human lung carcinoma tissue reacted with GRB2 Antibody (Y209), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.

 

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