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Home All anti-CASP3 antibodies
Anti-CASP3 Antibody CPP32 4-1-18
TrueMAB™ Antibodies - Made against Authentic Protein Antigens
* Buy one primary antibody, get 50% off a GAPDH loading control antibody.
Also for CASP3 (NM_032991)
OriGene Data
| Full-length recombinant human Caspase 3 protein. |
| CPP32 4-1-18 |
IgG2a kappa |
| human |
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| WB |
WB: 1:500-1: 1000 |
| 0.1% sodium azide |
| Affinity purified (Protein A or G Sepharose) |
Reference Data
| Homo sapiens caspase 3, apoptosis-related cysteine peptidase (CASP3), transcript variant beta |
| CPP32; CPP32B; SCA-1 |
| NP_116786 |
| Caspases are cysteine proteases, expressed as inactive precursors, that mediate apoptosis by proteolysis of specific substrates. Caspases have the ability to cleave after aspartic acid residues. There are two classes of caspases involved in apoptosis; initiators (activation by receptor cluster) and effectors (activation by mitochondrial permeability transition). Proapoptotic signals autocatalytically activate initiator caspases, such as Caspase-8 and Caspase-9. Activated initiator caspases then process effector caspases, such as Caspase-3 and Caspase-7, which in turn cause cell collapse. |
Apoptosis MAPK signaling pathway |
* Shipping is in business days
* OriGene provides validated application data and protocol, with money back guarantee.
WB Image
HEK293T cells were transfected with the pCMV6-ENTRY control or pCMV6-ENTRY CASP3 (RC204444) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-CASP3.
WB Image
Western blot detection of Capsase (19 and 35 kDa) from HEK293 cell extract. Lanes 1 and 2 contain inactive and active Capsase, respectively
Conjugation Services
OriGene provides conjugation services of TrueMAB antibodies with the following molecules:
- HRP
- Biotin
- PE
- FITC
- DyLight® 488
- DyLight® 550
- DyLight® 594
- DyLight® 633
* DyLight is a trademark of Thermo-Fisher Scientific
Bulk Order
OriGene offers bulk sizes of TrueMAB antibodies in both the BSA/glycerol formulation and the carrier-free (BSA/glycerol-free) formulation.
Contact us with your conjugation/bulk request: antibody@origene.com or 888-267-4436 (Tech Support)
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