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Anti-CASP3 Antibody CPP32 4-1-18
Also for CASP3 (NM_032991)
|Full-length recombinant human Caspase 3 protein.|
||0.5~1.0 mg/ml (Lot Dependent)
||WB: 1:500-1: 1000
|0.1% sodium azide|
|Affinity purified (Protein A or G Sepharose)
|Homo sapiens caspase 3, apoptosis-related cysteine peptidase (CASP3), transcript variant beta|
|CPP32; CPP32B; SCA-1|
|Caspases are cysteine proteases, expressed as inactive precursors, that mediate apoptosis by proteolysis of specific substrates. Caspases have the ability to cleave after aspartic acid residues. There are two classes of caspases involved in apoptosis; initiators (activation by receptor cluster) and effectors (activation by mitochondrial permeability transition). Proapoptotic signals autocatalytically activate initiator caspases, such as Caspase-8 and Caspase-9. Activated initiator caspases then process effector caspases, such as Caspase-3 and Caspase-7, which in turn cause cell collapse.|
MAPK signaling pathway
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Western blot detection of Capsase (19 and 35 kDa) from HEK293 cell extract. Lanes 1 and 2 contain inactive and active Capsase, respectively
Immunohistochemistry-Paraffin: Caspase 3 Antibody (CPP32 4-1-18) - Rat epithelial cells of the tongue base. Antigen retrieval method: Citrate buffer.