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Home Antibody All anti-LOX antibodies

Anti-LOX Antibody

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA301771
  • Rabbit Polyclonal Antibody against LOX
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC400843) , 20ug
50ul 325 In Stock
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WB(1)
IHC(1)
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Also for LOX (NM_002317)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenA cocktail of two synthetic peptides; one made to a region of the human LOX protein within residues 300-400 and one within residues 200-300
Clone Name IsotypeIgG
Species Reactivityhuman, mouse, rat, cow, porcine ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB, IHC Suggested DilutionsWB: 1: 1000-1:5000, IHC: 10-20 ug/ml
BufferTris-glycine, 150mM NaCl and 0.02% sodium azide
Purification Affinity purified

Reference Data

Target NameHomo sapiens lysyl oxidase (LOX), transcript variant 1
Alternative NameMGC105112
Database LinkNP_002308
FunctionLysyl oxidase (LOX), a copper-containing amine oxidase, belongs to a heterogeneous family of enzymes that oxidize primary amine substrates to reactive aldehydes. It plays a vital role in the formation and repair of the extracellular matrix. In addition, LOX is a multifunctional enzyme having diverse biological functions such as developmental regulation, tumor suppression, cell motility, and cellular senescence. The secreted form of LOX is responsible for the invasive properties of hypoxic human cancer cells. Thus, it is essential for hypoxia-induced metastasis and is a good therapeutic target for preventing and treating metastases.
Related Pathway

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WB Image
Detection of LOX in mouse kidney lysate, ECL detection was 15 sec
IHC Image
Human placental villi, 40X. Staining of placental trophoblasts

 

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